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當(dāng)前位置:主頁 > 產(chǎn)品中心 > > 抗體/抗原 >Anti-hnRNP K antibody EP943Y (ab52600)抗核糖核蛋白K抗體

Anti-hnRNP K antibody EP943Y (ab52600)抗核糖核蛋白K抗體

簡要描述:Anti-hnRNP K antibody [EP943Y] (ab52600)抗核糖核蛋白K抗體
貨號:ab52600
廠家:Abcam公司
規(guī)格:40ul/100ul
保存溫度:-20℃ 和 2~8℃
貨期:現(xiàn)貨2~5天,期貨2-3周

  • 產(chǎn)品型號:ab52600
  • 廠商性質(zhì):代理商
  • 更新時間:2017-02-01
  • 訪  問  量:1584
詳細(xì)介紹

咨詢:  (重慶) (貴陽)

Anti-hnRNP K antibody [EP943Y] (ab52600)抗核糖核蛋白K抗體產(chǎn)品信息:

  • Product nameAnti-hnRNP K antibody [EP943Y]
  • Description

    Rabbit monoclonal [EP943Y] to hnRNP K

  • SpecificityThis antibody detects both phosphorylated and unphosphorylated hnRNP K.
  • Tested applicationsWB, IP, IHC-P, ICC/IF
  • Species reactivity

    Reacts with: Mouse, Rat, Human

  • Immunogen

    A synthetic peptide corresponding to residues near the N-terminus of human hnRNP.

  • Positive control
    • Jurkat cell lysate; HeLa cells; Human breast carcinoma tissue.
  • General notesProduced under U.S. Patent No. 5,675,063.

Properties

  • FormLiquid
  • Storage instructionsStore at -20°C. Stable for 12 months at -20°C
  • Storage bufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • PurityTissue culture supernatant
  • Clonality Monoclonal
  • Clone numberEP943Y
  • IsotypeIgG
  • Research Areas
    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • RNA Processing
    • Other

Applications

Our Abpromise guarantee covers the use of ab52600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

ApplicationNotes
WBWB: 1/100000. Detects a band of approximay 60 kDa (predicted molecular weight: 51 kDa).
IPIP: 1/50.
IHC-PIHC-P: Use at an assay dependent dilution.
ICC/IFICC/IF: 1/100 - 1/250.

Target

  • FunctionOne of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA.
  • Sequence similaritiesContains 3 KH domains.
  • Post-translational
    modificationsArg-296 and Arg-299 are dimethylated, probably to asymmetric dimethylarginine.
  • Cellular localizationCytoplasm. Nucleus > nucleoplasm. In case of ASFV infection, there is a shift in the localization which becomes predominantly nuclear.
  • Database links

    • Entrez Gene: 3190 Human
    • Entrez Gene: 15387 Mouse
    • Entrez Gene: 117282 Rat
    • Omim: 600712 Human
    • SwissProt: P61978 Human
    • SwissProt: P61979 Mouse
    • SwissProt: P61980 Rat
    • Unigene: 522257 Human

    see all

  • Alternative names

    • CSBP antibody
    • dC stretch binding protein antibody
    • FLJ41122 antibody

    see all

Anti-hnRNP K antibody [EP943Y] images

  • Western blot - hnRNP K antibody [EP943Y] (ab52600)

    Western blot - hnRNP K antibody [EP943Y] (ab52600)

    Anti-hnRNP K antibody [EP943Y] (ab52600) at 1/100000 dilution + Jurkat cell lysate at 10 µg

    Secondary
    HRP-labelled goat anti-rabbit at 1/2000 dilution

    Predicted band size : 51 kDa
    Observed band size : ~60 kDa (why is the actual band size different from the predicted?)

  • Immunohistochemistry (Paraffin-embedded sections) - hnRNP K antibody [EP943Y] (ab52600)

    Immunohistochemistry (Paraffin-embedded sections) - hnRNP K antibody [EP943Y] (ab52600)

    Immunohistochemical staining of paraffin-embedded human breast carcinoma tissue using ab52600 at a dilution of 1/100-1/250.

  • Immunocytochemistry/ Immunofluorescence - hnRNP K antibody [EP943Y] (ab52600)

    Immunocytochemistry/ Immunofluorescence - hnRNP K antibody [EP943Y] (ab52600)

    Fluorescent immunostaining of HeLa cells using ab52600 at a dilution of 1/100-1/250.

公司介紹:

    Abcam位于英國的劍橋科學(xué)園,成立于1998年,專門生產(chǎn)和分銷研究型抗體。主要創(chuàng)立人Jonathan Milner和實驗室同事構(gòu)思成立一間了解科研人員需要的網(wǎng)上抗體公司,理念是Abcam銷售質(zhì)量高的抗體,并提供zui全面、誠實、時新的說明書,快速的送貨服務(wù),及高效率的顧客和服務(wù)。我們的在線目錄(m.lysqbb.cn) 已有差不多100,000種抗體和試劑,并不斷添加,供應(yīng)予百多個國家。Abcam200511月在倫敦證券交易所上市,在美國馬薩諸塞州、日本東京及香港均設(shè)有分公司。

    Abcam 一直致力加強(qiáng)產(chǎn)品線,為使研究員更容易找到蛋白質(zhì)研究試劑產(chǎn)品,在2011并購了美國的MitoSciences公司,加強(qiáng)了免疫分析方面的產(chǎn)品供應(yīng);同年也并購了英國的Ascent Scientific 公司,開展了生化試劑的供應(yīng)。在2012年,Abcam并購了美國的Epitomics 公司,成為一家有的RabMAbs® 供應(yīng)商。

    Abcam 的 目標(biāo)是給世界上的抗體建立zui大的在線目錄,為各地科學(xué)家提供*產(chǎn)品,成為各國科學(xué)界的重要伙伴。我們?yōu)樗挟a(chǎn)品提供來使客戶獲得預(yù)期的結(jié) 果。為提供高質(zhì)量的抗體來指向盡可能多的靶蛋白,我們盡所能在盡可能多的應(yīng)用和物種中檢測每種抗體。我們相信誠信才是上策,在我們的上會發(fā)布有關(guān)我們 每一種產(chǎn)品的盡可能多的信息。

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Abcamab11329Mouse monoclonal [AP180-I] to AP180100ul3996AP18抗體一抗

Abcamab1133Rabbit polyclonal to GABARAP100ul3996GABARAP抗體一抗

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